News & Activities

 

October 2019

 

Transcriptomics Explorer Launch

The Transcritpomics Explorer is a new tool that allows users to easily access cell-type information from mouse and human brains and to explore several custom-built visualizations of the data. Data supported by the U19 Zeng and U01 Lein BICCN grants is now available for visualization and analysis in the Transcriptomics Explorer.

Read more in the Allen Institute for Brain Science press release: Characterizing cell types in the mammalian brain.

 

September 2019

 

New Awardees

Congratulations to the awardees of eight new BICCN grants! Stay tuned for more information on the Teams page.

PI(s)

Institution

Title

Snyder-Mackler, Noah  (Contact); Platt, Michael L; Shendure, Jay Ashok

University of Washington Single cell transcriptional and epigenomic atlas of the macaque brain across the lifespan
Ecker, Joseph R (Contact); Behrens, M Margarita Salk Institute for Biological Studies Epigenomic cell-type classification and regulatory element identification in the human brain
Tilgner, Hagen Weill Medical Coll of Cornell Univ Single cell isoform expression across mouse brain regions and development
Nowakowski, Tomasz

University of California, San Francisco

Mapping Developmental Lineage Relationships in the Cerebral Cortex
Chung, Kwanghun  (Contact); Eichinger, Daniel J; Pino, Ignacio ; Zhu, Heng Massachusetts Institute of Technology Highly specific, renewable, and cost-effective antibody toolbox for 3D proteomic phenotyping of the brain
Tasic, Bosiljka Allen Institute Cell class- or type-specific viruses for brain-wide labeling and neural circuit examination
Regev, Aviv  (Contact); Eldar, Yonina Broad Institute Scaling up spatial RNA profiling with compressed sensing
Mueller, Ulrich  (Contact); Miller, Michael I Johns Hopkins University Accessible technologies for high-throughput, whole-brain reconstructions of molecularly characterized mammalian neurons

 

BICCN Workshop

A workshop was held September 23-25, 2019 in Jackson Hole, WY to facilitate joint analysis of anatomical and morphological data from across the BICCN. Co-organized by Dr. Pavel Osten and the BCDC, the workshop brought together BICCN researchers and external experts in neuroanatomy to tackle the challenge of establishing standardized data analysis approaches.

 

July 2019

 

New Awardee

A new data archive joins the BICCN consortium! “Distributed Archives for Neurophysiology Data Integration” (DANDI), led by Dr. Satrajit Ghosh at MIT, will house BICCN neurophysiology and MR data. More information to follow soon on the Teams page!

 

May 2019

 

Cell Registry Launch

The Cell Registry, a new tool for exploring BICCN data, was publicly launched in early May. See the announcement in the Allen Institute for Brain Science newsletter.

 

April 2019

 

BICCN Steering Committee Meeting & Workshop

The third BICCN Steering Committee meeting was held on NIH Campus in Bethesda, MD on April 10, 2019 in advance of the 5th annual BRAIN Initiative Investigators Meeting. Additionally, the BCDC lead coordination of a concurrent Data Mapping Workshop. In addition to moderated presentations and discussion from each major group within BICCN, the Steering Committee meeting included breakout sessions on: transgenic and viral tools; human and non-human primate progress and planning; and cloud-native pipelines.

The Data Mapping Workshop was a hands-on hack-a-thon style event to address the myriad challenges in accurate image modality definition, registration, and mapping, with the specific outcome of getting spatial features suitable to support inclusion of BICCN data into the Integrated Data Set.

 

November 2018

 

BICCN Steering Committee Meeting

Over 100 BICCN members and affiliates assembled for the biannual BICCN Steering Committee meeting on November 2, 2018 on the UC San Diego campus. With coordination by the BCDC, the agenda included sessions on the Mini-Atlas projects; the Common Coordinate Framework; BCDC roadmap; BICCN challenges; Data workflow challenges; and outreach efforts. Breakout sessions on Mouse CCF, human and non-human primate research, and BCDC Infrastructure/Service Ingestion facilitated focused, stakeholder-lead discussion.

 

August 2018

 

BICCN Portal Debut

The BICCN Portal debuted in August 2018, supporting the first public release of BICCN data. The BICCN Portal serves as a community entry page for all BICCN related data; it features an overview of the consortium and its mission, profiling each of the major BICCN groups, as well as description of the primary data modalities and scope generated.
See the NIH announcement for the BICCN Portal debut.

 

April 2018

 

BRAIN Initiative Meeting

BICCN members were key participants of the 4th annual BRAIN Initiative Investigators Meeting held in Bethesda, MD on April 9-12, 2018.

 

March 2018

 

BICCN Workshop

On March 22-23, 2018 the BCDC and Allen Institute held a workshop with over 50 BICCN affiliated scientists with the intent to inform, educate, and collaborate with BICCN members in the areas of data analysis and integration.

 

November 2017

 

BICCN Kickoff

The BICCN Kickoff Meeting was held November 11, 2017 at the Howard Hughes Janelia Farms Research Campus. Organized by the BCDC, the meeting brought together the BICCN Steering Committee for initial planning for BICCN collaborations and strategy.