R24 - Ropelewski

A Confocal Fluorescence Microscopy Brain Data Archive

The Brain Image Library (BIL) is a national public resource enabling researchers to deposit, analyze, mine, share and interact with large brain image datasets. BIL encompasses the deposition of datasets, the integration of datasets into a searchable web-accessible system, the redistribution of datasets, and a computational enclave to allow researchers to process datasets in-place and share restricted and pre-release datasets.

The BIL is operated as a partnership between the Biomedical Applications Group at the Pittsburgh Supercomputing Center, the Center for Biological Imaging at the University of Pittsburgh and the Molecular Biosensor and Imaging Center at Carnegie Mellon University.   Shown in A and B above are high resolution confocal images as examples of the type that the repository will hold.

Project Leadership

Alexander Ropelewski (Principal Investigator)
Director Biomedical Applications Group
Pittsburgh Supercomputing Center
https://www.psc.edu/staff/ropelewski

Simon Watkins (Principal Investigators)
Distinguished Professor and Vice Chair Cell Biology
Professor Immunology
Director Center for Biologic Imaging
University of Pittsburgh
http://www.cbp.pitt.edu/faculty/watkins.html

Marcel Bruchez (Principal Investigator)
Professor, Biological Sciences and Chemistry
Director, Molecular Biosensors and Imaging Center
Carnegie Mellon University
https://www.cmu.edu/bio/people/faculty/bruchez.html

Kathy Benninger
Manager Of Networking Research
Pittsburgh Supercomputing Center
https://psc.edu/index.php/141-about/staff/2514-benninger

Jacob Czech
Senior Scientific Research Programmer
Pittsburgh Supercomputing Center
http://mcell.org/people/jacob.html

Greg Hood
Senior Computer Scientist
Pittsburgh Supercomputing Center
https://www.psc.edu/staff

Greg Fisher
Senior Research Scientist
Carnegie Mellon University
http://pathways.mbic.cmu.edu/people/

Derek Simmel
Grid Computing Specialist
Pittsburgh Supercomputing Center
https://www.psc.edu/staff/simmel

Alan Watson
Research Assistant Professor
Department of Cell Biology
University of Pittsburgh
http://www.cbp.pitt.edu/faculty/watson.html

Art Wetzel
Principal Computer Scientist
Pittsburgh Supercomputing Center
https://www.brainimagelibrary.org/people.html

Project Data Types

  • High-resolution volumetric brain data from the BRAIN Initiative Cell Census network and other researchers.  
  • Data Modalities/assays housed in the library include: Fmost, Mouselight, OLST, Virus Tracing, and others.

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